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PNA RESEARCH CASE LIBRARYNeurological Rehabilitation · 2025

A structured rehabilitation program for functional recovery in Guillain–Barré syndrome: a case report

Neda M. Yousef, Daniel Kayode Adejumo, Animesh Hazari, Praveen Kumar Kandakurti

Journal of Medical Case Reports · 2025 · DOI: 10.1186/s13256-025-05545-z

Free full text available · Open-access full text on PubMed Central; use the source article's licence for any reuse.

THE CASE IN PLAIN ENGLISH

What happened?

A 40-year-old woman with Guillain–Barré syndrome developed profound weakness affecting all four limbs and required extensive assistance with daily activities. The report follows a structured, goal-based rehabilitation programme over four months after acute medical treatment.

Clinical findings

  • The patient initially had severe generalized weakness, restricted range in several joints, marked tightness in selected muscle groups and poor supported sitting balance.
  • She was dependent for basic activities and required substantial help with bed mobility and transfers.
  • The authors describe recurrent flare-ups during the rehabilitation period, making reassessment and adjustment important.

Rehabilitation described in the report

  • The programme combined range-of-motion work, prolonged stretching, active-assisted exercise, trunk control, bed mobility practice, sitting balance, progressive strengthening and functional task training.
  • Treatment was advanced from passive and assisted activity toward more active movement and assisted sit-to-stand according to the patient's ability.
  • The published programme includes specific repetitions and techniques; clinicians should consult the original paper and individualize care rather than copy its dose.

Reported outcomes

  • After four months, the patient could sit unsupported, move from side-lying to sitting with minimal assistance and stand with partial assistance.
  • The authors reported improved muscle grades, reduced tightness and improvement on the Guillain–Barré disability scale.

Clinical lessons to consider

  • Severe neurological rehabilitation needs staged goals: positioning and range first when required, then trunk control, bed mobility, transfers and functional strength.
  • Measure changes in assistance level and everyday function, not just isolated muscle grades.
  • Guillain–Barré recovery can fluctuate; monitor fatigue, respiratory status and medical stability with the wider team.

Limitations — what this case cannot tell us

  • Single case with a complex clinical course; improvement cannot be attributed to one treatment component.
  • The programme is not a universal protocol for every GBS subtype or severity level.

Original source

Neda M. Yousef, Daniel Kayode Adejumo, Animesh Hazari, Praveen Kumar Kandakurti. “A structured rehabilitation program for functional recovery in Guillain–Barré syndrome: a case report.” Journal of Medical Case Reports, 2025. DOI: 10.1186/s13256-025-05545-z

View the original publication

This page is an independently written educational summary, not a reproduction of the full paper. Check the original article for complete methods, outcome tables, references and licensing.