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KneePatellofemoral / Load-RelatedStrong evidence

Patellofemoral Pain

Peripatellar or retropatellar pain aggravated by loaded knee flexion such as stairs, squatting, running or prolonged sitting.

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Structures Involved

  • Patellofemoral joint and surrounding tissues; pain is multifactorial and not necessarily due to maltracking.

Mechanism / Why It Happens

  • Training-load spike
  • Reduced capacity relative to running, jumping or squat demand
  • Multiple individual biomechanical and contextual contributors

Classification / Grades

  • Activity-related patellofemoral pain
  • Assess coexisting instability, cartilage injury or patellar tendinopathy

Symptoms

  • Diffuse anterior/peripatellar pain
  • Pain with stairs, squat, running or prolonged sitting
  • Usually no large acute effusion

Clinical Signs

  • Pain during squat/step-down
  • Possible hip/knee strength or movement-control deficits
  • Patellar mobility is variable and not diagnostic alone

Red Flags & Referral Clues

  • Large acute effusion or traumatic onset
  • True locking
  • Patellar dislocation
  • Fever/hot joint or inability to weight bear

Diagnostic Examination

How to perform the tests — step by step

Each test includes patient setup, therapist position, hand placement, exact performance, positive finding and clinical interpretation.

Single-Leg Squat

Assess functional load tolerance and movement strategy while reproducing familiar anterior knee pain.

Patient position

Patient stands on one leg near support and performs controlled shallow-to-deeper squat; observe pelvis, trunk and knee.

Therapist position

Position yourself to observe and stabilise the relevant segment without forcing the movement.

Hand placement

Use comfortable, controlled contact appropriate to the test; avoid painful compression or excessive force.

How to perform

  1. 1Explain the test and obtain consent.
  2. 2Screen contraindications and compare sides when appropriate.
  3. 3Perform the movement slowly and apply only the required resistance or stress.
  4. 4Record familiar symptom reproduction, range, strength and side-to-side difference.

Positive sign

Familiar peripatellar pain during loaded knee flexion.

Interpretation

Supports load-related PFP when history fits; movement appearance alone does not diagnose cause.

Clinical note: A special test modifies clinical probability; it does not confirm a diagnosis in isolation.

Differential Diagnosis

  • Patellar tendinopathy
  • Meniscal injury
  • Patellofemoral instability
  • Knee OA
  • Referred hip pain

Investigations / Imaging

  • Usually clinical; imaging not routinely needed for typical PFP.
  • Radiographs/MRI if trauma, recurrent instability, large effusion, locking or atypical persistent symptoms.

Complete Rehabilitation Plan

From protection to full function

Phase 1 — Protection, Education & Symptom-Guided Loading

Address safety, settle excessive irritability and maintain useful movement.

What to do

  • Explain load-capacity relationship and adjust painful running/jumping temporarily
  • Continue tolerable activity
  • Begin knee and/or hip strengthening at manageable range

Exercise dosage

  • Isometric quadriceps or shallow squat: 4–5 x 20–30 seconds
  • Temporarily reduce provoking volume, not all activity

Progress when

  • Daily function is stable or improving.
  • No new red flags or progressive neurological deficit.
  • Exercise response returns to baseline by the following day.

Phase 2 — Mobility, Strength & Capacity

Restore the specific strength, mobility and control required by the condition.

What to do

  • Progress quadriceps and hip strengthening
  • Add step-down, squat and single-leg control
  • Use running retraining only when relevant to individual deficits

Exercise dosage

  • Squat/leg press: 3 x 8–12
  • Hip abductor/external rotator strengthening: 2–3 x 10–15, 2–3 days/week

Progress when

  • Target movement and resistance are tolerated with good quality.
  • Functional capacity is improving without sustained symptom flare.
  • Progression is based on objective performance and patient goals.

Phase 3 — Functional Restoration & Return to Activity

Rebuild real-world, occupational or sporting capacity.

What to do

  • Graded return to running, jumping and stairs
  • Progress volume, speed and hills separately
  • Maintain strengthening to reduce recurrence

Exercise dosage

  • Hops/jumps: 2–4 sets of 5–10 quality reps
  • Run-walk progression with rest/recovery days

Progress when

  • Condition-specific return criteria are met.
  • Full task exposure is completed progressively.
  • No clinically meaningful deterioration during the following 24 hours.

Manual Therapy — Role & Application

  • Patellar taping or mobilisation may provide short-term adjunctive relief in selected patients.
  • Manual therapy should not replace hip and knee exercise.

Modalities — Use / Avoid

  • Foot orthoses may help selected patients short term when matched to response.
  • Routine passive electrotherapy is not a core intervention.

Return / Discharge Criteria

  • Stairs and single-leg squat tolerated
  • Running/jumping progressed without meaningful flare
  • Quadriceps and hip capacity appropriate for goals

Common Clinical Mistakes

  • Focusing on static knee valgus as the diagnosis
  • Only strengthening VMO
  • Stopping all running indefinitely
  • Ignoring training load

Clinical Pearls

  • Combined hip- and knee-targeted exercise is supported by the PFP guideline.
  • Use the patient's pain response and functional goals to select exercise range.

Continue learning

Connect assessment with management

Use the related PNA learning pathways to explore examination techniques and structured rehabilitation. A test result should always be interpreted alongside the history, full examination and clinical presentation.

Evidence sources

Use these sources as a starting point for clinical learning. A reference being listed here does not, by itself, establish that every recommendation on this page is strongly supported. Check the original publication, study design, population and limitations before applying findings to an individual patient.

Educational resource only. Tests and treatment plans must be adapted to the individual patient, irritability, comorbidities, surgical restrictions and local scope-of-practice requirements.